Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MYLK | Q15746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30891958 | 0.74 | MEN1 (0.41) | MAPTMEN1KMT2ANLRP3L3MBTL1 | |
| SCHEMBL31166655 | 0.73 | PRKCE (0.36) | MAPTPRKCETDP1MYLKMEN1 | |
| SCHEMBL31359535 | 0.73 | MAOB (0.39) | TDP1NLRP3LMNA | |
| SCHEMBL31359529 | 0.69 | NLRP3 (0.37) | MAPTPRKCETDP1MYLKMEN1 | |
| SCHEMBL31359530 | 0.69 | NLRP3 (0.34) | MAPTALDH1A1NLRP3PTGS2 | |
| SCHEMBL16597268 | 0.68 | MAPT (0.35) | MAPTMEN1KMT2ANLRP3GNG2 | |
| SCHEMBL12697423 | 0.67 | CA2 (0.46) | MAPTPRKCETDP1MYLKMEN1 | |
| SCHEMBL27747018 | 0.67 | PTPN1 (0.63) | MAPTPRKCETDP1MYLKMEN1 | |
| SCHEMBL2052981 | 0.67 | MEN1 (0.41) | MAPTMEN1KMT2AALDH1A1NLRP3 | |
| SCHEMBL23674358 | 0.65 | MEN1 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121586712-A | Novel compounds | 豪夫迈·罗氏有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025026882-A1 | NOVEL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-02-06 | — | — | WO | disclosed |