Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.62 |
| ▸ | MAPT | P10636 | 13/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.62 |
| ▸ | NPC1 | O15118 | 10/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368730 | 0.77 | RAB9A (1.00) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5329732 | 0.74 | RAB9A (0.80) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7238213 | 0.74 | RAB9A (0.97) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL18114078 | 0.73 | MAPT (0.65) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7230888 | 0.72 | RAB9A (1.00) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL1771825 | 0.71 | ALDH1A1 (0.79) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23610361 | 0.69 | ALDH1A1 (0.83) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL172246 | 0.69 | ALDH1A1 (1.00) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL29654190 | 0.69 | RAB9A (0.70) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL29085894 | 0.68 | RAB9A (0.65) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004441-A1 | N-(5-Membered Aromatic Ring)-Amido Anti-Viral Compounds | SCHMITZ FRANZ ULRICH | 2010-01-07 | — | — | US | disclosed |
| US-7595398-B2 | N-(5-membered aromatic ring)-amido anti-viral compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2009-09-29 | — | — | US | disclosed |
| EP-1971597-A2 | N-(5-MEMBERED HETEROAROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007070600-A2 | N-(5-MEMBERED HETEROAROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004441-A1 | N-(5-Membered Aromatic Ring)-Amido Anti-Viral Compounds | ZC3HAV1, ZC3HAV1L, HAVCR2 | RAB9A 487/4885MAPT 1615/4885SMN1; SMN2 1431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.