Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713032 | 0.82 | SMN1; SMN2 (0.49) | RIPK1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3971428 | 0.74 | NPC1 (0.45) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL27078358 | 0.71 | ALOX5 (0.47) | ALDH1A1L3MBTL1CETP | |
| SCHEMBL2034512 | 0.70 | PPIB (0.51) | ALDH1A1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL6393090 | 0.70 | ALDH1A1 (0.53) | RIPK1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11640091 | 0.70 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL17030320 | 0.70 | MEN1 (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL10627501 | 0.70 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL8316594 | 0.69 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28663669 | 0.69 | ALDH1A1 (0.51) | GAAALOX12CYP2C19ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176820-A | Tricyclic compounds as MAT2A inhibitors | 艾立康药业股份有限公司 | 2024-12-24 | — | — | CN | disclosed |