Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361233 | 0.90 | — | — | |
| SCHEMBL31361119 | 0.86 | KDM4E (0.38) | PDE4BKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL31361218 | 0.85 | MBOAT4 (0.32) | MBOAT4 | |
| SCHEMBL31361126 | 0.83 | MBOAT4 (0.34) | MBOAT4KDM4E | |
| SCHEMBL30986426 | 0.81 | KDM4E (0.33) | KDM4E | |
| SCHEMBL31361174 | 0.81 | KDM4E (0.33) | MBOAT4PDE4BPDE4DKDM4EMEN1 | |
| SCHEMBL31361121 | 0.81 | POLB (0.32) | KDM4EALDH1A1 | |
| SCHEMBL31361202 | 0.80 | GRM2 (0.33) | PDE4BKDM4E | |
| SCHEMBL31361250 | 0.79 | KDM4E (0.31) | KDM4EMEN1KMT2A | |
| SCHEMBL31078137 | 0.78 | RPS6KA5 (0.40) | KDM4EPDE10AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746965-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017041-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |