Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361141 | 0.81 | MBOAT4 (0.33) | KDM4EMBOAT4PDE4BPDE4DMEN1 | |
| SCHEMBL31361145 | 0.77 | GRM2 (0.40) | KDM4EKMT2AHTTGRM2 | |
| SCHEMBL30986468 | 0.74 | — | — | |
| SCHEMBL25318266 | 0.73 | MEN1 (0.39) | KDM4EMEN1ALDH1A1KMT2AHTT | |
| SCHEMBL31153160 | 0.73 | MEN1 (0.39) | KDM4EMEN1ALDH1A1KMT2AHTT | |
| SCHEMBL31361222 | 0.72 | KDM4E (0.36) | KDM4EALDH1A1HTT | |
| SCHEMBL31361215 | 0.71 | KDM4E (0.33) | KDM4EHTT | |
| SCHEMBL31361233 | 0.71 | — | — | |
| SCHEMBL31361117 | 0.71 | KDM4E (0.38) | KDM4E | |
| SCHEMBL31078206 | 0.69 | RPS6KA5 (0.35) | KDM4EMBOAT4KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746965-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017041-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |