Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361289 | 0.91 | GRM2 (0.40) | GRM2NOTUMKDM4EAR | |
| SCHEMBL31361126 | 0.81 | MBOAT4 (0.34) | GRM2KDM4E | |
| SCHEMBL31078137 | 0.80 | RPS6KA5 (0.40) | KDM4EAR | |
| SCHEMBL25867032 | 0.79 | MEN1 (0.36) | KDM4E | |
| SCHEMBL30986426 | 0.79 | KDM4E (0.33) | KDM4E | |
| SCHEMBL29311582 | 0.79 | KDM4E (0.33) | KDM4E | |
| SCHEMBL31361119 | 0.78 | KDM4E (0.38) | KDM4EAR | |
| SCHEMBL25318477 | 0.76 | MEN1 (0.37) | KDM4E | |
| SCHEMBL30508839 | 0.76 | ALDH1A1 (0.33) | KDM4E | |
| SCHEMBL30508578 | 0.76 | MEN1 (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746965-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017041-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |