Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673039 | 1.00 | MAPT (0.58) | MAPTKMT2AMEN1CA1CA2 | |
| SCHEMBL27639258 | 0.85 | MAPT (0.54) | MAPTKMT2AMEN1CA1CA2 | |
| SCHEMBL16554589 | 0.84 | CA12 (0.65) | CA1CA2CA12CA7CA9 | |
| SCHEMBL7612403 | 0.82 | MAPT (0.54) | MAPTKMT2AMEN1CA1CA2 | |
| SCHEMBL17512372 | 0.82 | MAPT (0.50) | MAPTKMT2AMEN1CA1CA2 | |
| SCHEMBL8922678 | 0.81 | KDM4E (0.59) | MAPTKMT2ACA1CA2CA12 | |
| SCHEMBL5152555 | 0.81 | CA1 (0.65) | MAPTKMT2AMEN1CA1CA2 | |
| SCHEMBL8698365 | 0.81 | ALDH1A1 (0.65) | MAPTKMT2AMEN1CA1CA2 | |
| Veratric Acid Methyl Ester SCHEMBL29573244 | 0.80 | MAPT (0.86) | MAPTKMT2AMEN1CA1CA2 | |
| Veratric Acid Methyl Ester SCHEMBL2050732 | 0.80 | MAPT (0.86) | MAPTKMT2AMEN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |