Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 4/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361328 | 0.92 | MAT2A (0.42) | MAT2AALDH1A1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL31361350 | 0.83 | MAT2A (0.42) | MAT2AALDH1A1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL31361444 | 0.80 | MAT2A (0.41) | MAT2AALDH1A1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL31361401 | 0.79 | MAT2A (0.41) | MAT2AALDH1A1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL31361411 | 0.79 | MAT2A (0.52) | MAT2AALDH1A1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL31361266 | 0.78 | MEN1 (0.48) | MAT2AALDH1A1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL31361299 | 0.78 | MAT2A (0.41) | MAT2AALDH1A1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL19936241 | 0.77 | MAT2A (0.56) | MAT2AALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL19972068 | 0.77 | MAT2A (0.52) | MAT2AALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL31361321 | 0.76 | MAT2A (0.41) | MAT2AALDH1A1SMN1; SMN2NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |