Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 11/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361294 | 0.86 | NPSR1 (0.43) | MAT2ANPY5RALDH1A1NPSR1LMNA | |
| SCHEMBL31361457 | 0.85 | MAT2A (0.41) | MAT2ANPY5RALDH1A1NPSR1TSHR | |
| SCHEMBL31361444 | 0.81 | MAT2A (0.41) | MAT2ANPY5RALDH1A1NPSR1LMNA | |
| SCHEMBL31361328 | 0.80 | MAT2A (0.42) | MAT2ANPY5RALDH1A1POLBNPSR1 | |
| SCHEMBL31361397 | 0.79 | MAT2A (0.42) | MAT2ANPY5RALDH1A1POLBNPSR1 | |
| SCHEMBL19936241 | 0.78 | MAT2A (0.56) | MAT2ANPY5RALDH1A1LMNAMAPK1 | |
| SCHEMBL19972068 | 0.78 | MAT2A (0.52) | MAT2AALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL19927343 | 0.77 | MAT2A (0.49) | MAT2ANPY5RALDH1A1HSD17B10KDM4E | |
| SCHEMBL19927385 | 0.76 | MAT2A (0.50) | MAT2AALDH1A1KDM4E | |
| SCHEMBL19927470 | 0.76 | MAT2A (0.50) | MAT2AALDH1A1NPSR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |