Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CSK | P41240 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361458 | 0.86 | HTT (0.42) | MAT2AMAPTSMN1; SMN2TRPA1GAA | |
| SCHEMBL31361355 | 0.84 | MAPT (0.40) | MAT2AMAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL31361444 | 0.81 | MAT2A (0.41) | MAT2AMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31361321 | 0.80 | MAT2A (0.41) | MAT2AMAPTSMN1; SMN2ADRA1AADRA1B | |
| SCHEMBL19936241 | 0.78 | MAT2A (0.56) | MAT2AGAAKDM4EMEN1KMT2A | |
| SCHEMBL19926567 | 0.77 | MAT2A (0.52) | MAT2AMAPTSMN1; SMN2HPGDKDM4E | |
| SCHEMBL31361294 | 0.77 | NPSR1 (0.43) | MAT2AMAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL31361416 | 0.76 | TUBB4A (0.41) | MAT2ASMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL31361364 | 0.76 | KMT2A (0.40) | MAT2ASMN1; SMN2HPGDKDM4EMEN1 | |
| SCHEMBL19927470 | 0.76 | MAT2A (0.50) | MAT2AMAPTSMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |