Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 4/20 | 0.34 |
| ▸ | PDE8B | O95263 | 6/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | PDE8A | O60658 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361732 | 0.83 | TLR7 (0.41) | HRH3ERBB2EPHA2KDREPHB4 | |
| SCHEMBL31361676 | 0.83 | TLR7 (0.41) | HRH3ERBB2EPHA2KDREPHB4 | |
| SCHEMBL31361712 | 0.80 | DRD4 (0.41) | HRH3CCR2KCNH2ADORA3ADORA2A | |
| SCHEMBL31361626 | 0.78 | IRAK4 (0.38) | HRH3CCR2KCNH2 | |
| SCHEMBL1704144 | 0.78 | MAPT (0.39) | PDE8BLMNAMAPT | |
| SCHEMBL29676590 | 0.76 | PPIB (0.36) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL22261043 | 0.74 | TDP1 (0.47) | PDE8BMAPT | |
| SCHEMBL20461176 | 0.73 | MAPT (0.32) | LMNAMAPT | |
| SCHEMBL16652473 | 0.73 | EPHA2 (0.43) | ERBB2EPHA2EPHB4LMNAMAPT | |
| SCHEMBL31361669 | 0.73 | EPHA2 (0.43) | ERBB2EPHA2EPHB4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |