Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704144 | 0.81 | MAPT (0.39) | — | |
| SCHEMBL31361676 | 0.81 | TLR7 (0.41) | IRAK4HRH3 | |
| SCHEMBL31361732 | 0.81 | TLR7 (0.41) | IRAK4HRH3 | |
| SCHEMBL31361652 | 0.80 | ALDH1A1 (0.38) | IRAK4HRH3KCNH2CCR2 | |
| SCHEMBL31361587 | 0.78 | HRH3 (0.39) | HRH3KCNH2CCR2 | |
| SCHEMBL22261043 | 0.77 | TDP1 (0.47) | — | |
| SCHEMBL29676590 | 0.76 | PPIB (0.36) | — | |
| SCHEMBL31361669 | 0.70 | EPHA2 (0.43) | — | |
| SCHEMBL16652473 | 0.70 | EPHA2 (0.43) | — | |
| SCHEMBL20461176 | 0.70 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |