Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361732 | 1.00 | TLR7 (0.41) | TLR7SLC6A2WNT1GSK3BDYRK1A | |
| SCHEMBL31361587 | 0.83 | HRH3 (0.39) | TLR7HRH3EPHA2MAPTLMNA | |
| SCHEMBL31361626 | 0.81 | IRAK4 (0.38) | IRAK4HRH3 | |
| SCHEMBL1704144 | 0.80 | MAPT (0.39) | MAPTLMNAALDH1A1PKML3MBTL1 | |
| SCHEMBL31361681 | 0.79 | ALDH1A1 (0.42) | TLR7SLC6A2WNT1GSK3BDYRK1A | |
| SCHEMBL29676590 | 0.79 | PPIB (0.36) | — | |
| SCHEMBL22261043 | 0.76 | TDP1 (0.47) | MAPTALDH1A1PKMMEN1KMT2A | |
| SCHEMBL1703769 | 0.76 | HDAC1 (0.47) | TLR7HRH3MAPTLMNAKDR | |
| SCHEMBL1665196 | 0.75 | KLKB1 (0.41) | TLR7SLC6A2IRAK4HRH3LMNA | |
| SCHEMBL31361733 | 0.75 | KLKB1 (0.41) | TLR7SLC6A2IRAK4HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |