Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28105414 | 0.87 | KHK (0.37) | JAK2JAK1TYK2JAK3KHK | |
| SCHEMBL16985462 | 0.84 | L3MBTL1 (0.37) | JAK2JAK1L3MBTL1BRAFF2 | |
| SCHEMBL16985304 | 0.83 | ROCK2 (0.37) | KHKL3MBTL1F2PLAUELANE | |
| SCHEMBL16985335 | 0.83 | ROCK2 (0.37) | KHKL3MBTL1F2PLAUELANE | |
| SCHEMBL15317792 | 0.83 | ROCK2 (0.37) | KHKL3MBTL1F2PLAUELANE | |
| SCHEMBL31361731 | 0.83 | L3MBTL1 (0.41) | L3MBTL1SLC18A3F2PLAUELANE | |
| Hydrochloric Acid SCHEMBL26643986 | 0.83 | L3MBTL1 (0.36) | JAK2JAK1L3MBTL1BRAFF2 | |
| Hydrochloric Acid SCHEMBL30475612 | 0.82 | CYP1A2 (0.38) | KHKL3MBTL1F2PLAUELANE | |
| Hydrochloric Acid SCHEMBL20476166 | 0.82 | CYP1A2 (0.38) | KHKL3MBTL1F2PLAUELANE | |
| Hydrochloric Acid SCHEMBL9951956 | 0.82 | CYP1A2 (0.38) | KHKL3MBTL1F2PLAUELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |