Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.42 |
| ▸ | JAK1 | P23458 | 3/20 | 0.42 |
| ▸ | JAK3 | P52333 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | CDK9 | P50750 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 5/20 | 0.41 |
| ▸ | FLT4 | P35916 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31361737 | 0.95 | HDAC3 (0.43) | JAK2JAK1JAK3HDAC3HDAC6 | |
| SCHEMBL31361679 | 0.83 | JAK1 (0.54) | JAK2JAK1JAK3HDAC3HDAC6 | |
| SCHEMBL30962741 | 0.81 | PDE4A (0.43) | JAK3TYK2LCKDHODHSRC | |
| SCHEMBL30962844 | 0.80 | EGFR (0.62) | JAK2JAK3TNK2LCKBTK | |
| SCHEMBL31361723 | 0.79 | JAK3 (0.47) | JAK2JAK1JAK3HDAC3HDAC6 | |
| SCHEMBL31361705 | 0.79 | JAK3 (0.47) | JAK2JAK1JAK3HDAC3HDAC6 | |
| SCHEMBL31361596 | 0.79 | JAK3 (0.47) | JAK2JAK1JAK3HDAC3HDAC6 | |
| SCHEMBL31361667 | 0.79 | JAK3 (0.47) | JAK2JAK1JAK3HDAC3HDAC6 | |
| SCHEMBL31361629 | 0.76 | KMT2A (0.47) | — | |
| SCHEMBL31361672 | 0.74 | PDE4A (0.43) | JAK3TYK2LCKDHODHSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |