SCHEMBL31361796

SCHEMBL31361796

CC(CCn1cnc2ccccc21)N(Cc1ccncc1)Cc1coc2c(ccc3ccccc32)c1=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 6/20 0.33
▸ FNTB P49356 6/20 0.33
▸ CYP17A1 P05093 1/20 0.33
▸ CYP19A1 P11511 1/20 0.33
▸ CYP11B1 P15538 1/20 0.33
▸ CYP11B2 P19099 1/20 0.33
▸ TDP1 Q9NUW8 2/20 0.32
▸ OPRM1 P35372 1/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ PTPN1 P18031 1/20 0.32
▸ AGER Q15109 2/20 0.32
▸ HTT P42858 2/20 0.31
▸ ALDH1A1 P00352 2/20 0.31
▸ PKM P14618 1/20 0.31
▸ APAF1 O14727 1/20 0.31
▸ KDM4E B2RXH2 2/20 0.31
▸ GAA P10253 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21592297 1.00 FNTA (0.33) FNTAFNTBCYP17A1CYP19A1CYP11B1
SCHEMBL21592291 0.83 KMT2A (0.35) CYP17A1CYP19A1CYP11B1CYP11B2TDP1
SCHEMBL21592282 0.75 CYP11B1 (0.40) CYP11B1CYP11B2KMT2AMEN1POLB
SCHEMBL21591545 0.75 SMN1; SMN2 (0.33) TDP1KMT2AMEN1POLBPTPN1
SCHEMBL21592285 0.75 KCNA5 (0.36) CYP17A1CYP19A1CYP11B1CYP11B2TDP1
SCHEMBL21591551 0.74 MEN1 (0.33) TDP1KMT2AMEN1POLBPTPN1
SCHEMBL21592298 0.74 KCNA5 (0.36) CYP11B1CYP11B2ALDH1A1KDM4ENPSR1
SCHEMBL31361799 0.71 ACHE (0.33) CYP11B1CYP11B2KMT2AMEN1POLB
SCHEMBL21591562 0.71 ACHE (0.33) CYP11B1CYP11B2KMT2AMEN1POLB
SCHEMBL21591431 0.70 CYP11B1 (0.48) CYP17A1CYP19A1CYP11B1CYP11B2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12162863-B2 Modulators of stimulator of interferon genes (STING) Ryvu Therapeutics S.A. (PL) 2024-12-10 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162863-B2 Modulators of stimulator of interferon genes (STING) STING1, IRF3, CGAS FNTA 1343/4885FNTB 861/4885CYP17A1 914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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