Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31362218 | 0.78 | HPGD (0.47) | CYP1A2MEN1KMT2AHPGDCCR5 | |
| SCHEMBL31159153 | 0.76 | NPSR1 (0.41) | ALOX5APCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19056655 | 0.76 | NPSR1 (0.41) | ALOX5APCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30681381 | 0.76 | DRD2 (0.47) | CYP1A2MEN1KMT2AALOX5APCYP2C19 | |
| SCHEMBL3061256 | 0.76 | DRD2 (0.47) | CYP1A2MEN1KMT2AALOX5APCYP2C19 | |
| SCHEMBL30390423 | 0.76 | DRD2 (0.47) | CYP1A2MEN1KMT2AALOX5APCYP2C19 | |
| SCHEMBL29571640 | 0.76 | DRD2 (0.47) | CYP1A2MEN1KMT2AALOX5APCYP2C19 | |
| SCHEMBL1760601 | 0.76 | DRD2 (0.47) | CYP1A2MEN1KMT2AALOX5APCYP2C19 | |
| SCHEMBL31599420 | 0.76 | NOTUM (0.41) | — | |
| SCHEMBL3634218 | 0.76 | KDM4E (0.50) | CYP1A2MEN1KMT2AHPGDCRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836054-B | IL4I1 inhibitors and methods of use | 默沙东有限责任公司 | 2024-12-10 | — | — | CN | disclosed |