Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | PDE8B | O95263 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | IL1B | P01584 | 2/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15575861 | 0.86 | OPRD1 (0.43) | PRMT5KDM1APDE8BCHEK2CCR5 | |
| SCHEMBL28538502 | 0.83 | PDE8B (0.40) | PRMT5KDM1APDE8BCHEK2OPRD1 | |
| SCHEMBL30336989 | 0.80 | KDM4E (0.50) | HPGDCCR5MEN1CYP1A2KMT2A | |
| SCHEMBL3634218 | 0.80 | KDM4E (0.50) | HPGDCCR5MEN1CYP1A2KMT2A | |
| SCHEMBL6495180 | 0.80 | CCR5 (0.48) | CCR5CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6495183 | 0.80 | CCR5 (0.48) | CCR5CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL30025877 | 0.78 | PDE8B (0.44) | PRMT5KDM1APDE8BCHEK2MEN1 | |
| SCHEMBL737331 | 0.78 | HPGD (0.57) | HPGDLMNAMEN1CYP1A2KMT2A | |
| SCHEMBL6496381 | 0.78 | PARP1 (0.53) | PRMT5CCR5MEN1KMT2AOPRK1 | |
| SCHEMBL31362205 | 0.78 | CYP1A2 (0.41) | HPGDCCR5MEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836054-B | IL4I1 inhibitors and methods of use | 默沙东有限责任公司 | 2024-12-10 | — | — | CN | disclosed |