Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31362437 | 0.81 | MEN1 (0.34) | MEN1KMT2AACACBNR1H2PTPN1 | |
| SCHEMBL31362279 | 0.81 | MEN1 (0.34) | MEN1KMT2AACACBNR1H2PTPN1 | |
| SCHEMBL31362592 | 0.80 | GPR119 (0.40) | MEN1KMT2AACACBNR1H2ALDH1A1 | |
| SCHEMBL31362446 | 0.80 | GPR119 (0.40) | MEN1KMT2AACACBNR1H2ALDH1A1 | |
| SCHEMBL19781282 | 0.77 | MEN1 (0.37) | MEN1KMT2AACACBNR1H2PTPN1 | |
| SCHEMBL19781607 | 0.77 | MEN1 (0.37) | MEN1KMT2AACACBNR1H2PTPN1 | |
| SCHEMBL29697602 | 0.70 | NR1H2 (0.45) | NR1H2GRM5ESR2 | |
| SCHEMBL22435395 | 0.70 | NR1H2 (0.45) | NR1H2GRM5ESR2 | |
| SCHEMBL31751317 | 0.69 | ESR2 (0.41) | NR1H2GRM5GPR119ESR2 | |
| SCHEMBL22738387 | 0.69 | GRM5 (0.40) | MEN1KMT2AGRM5PTPN1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |