SCHEMBL31362968

SCHEMBL31362968

COC(=O)c1c(Oc2cccc(Br)c2)cnn1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.49
MAPT P10636 3/20 0.49
GAA P10253 2/20 0.49
RECQL P46063 2/20 0.49
CYP2C19 P33261 4/20 0.43
NPSR1 Q6W5P4 3/20 0.41
CYP2C9 P11712 3/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
ATM Q13315 1/20 0.41
HTT P42858 1/20 0.41
TSHR P16473 2/20 0.41
ICAM1 P05362 1/20 0.41
SELE P16581 1/20 0.41
EGFR P00533 2/20 0.40
ALDH1A1 P00352 3/20 0.40
KMT2A Q03164 1/20 0.40
ELANE P08246 1/20 0.39
IRAK4 Q9NWZ3 1/20 0.39
NCOA1 Q15788 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31362990 0.87 ICAM1 (0.42) CYP1A2MAPTGAARECQLCYP2C19
SCHEMBL31405514 0.84 CYP1A2 (0.46) CYP1A2MAPTGAARECQLCYP2C19
SCHEMBL31163172 0.84 CYP1A2 (0.46) CYP1A2MAPTGAARECQLCYP2C19
SCHEMBL31362973 0.75 MAPT (0.35) CYP1A2MAPTGAARECQLCYP2C19
SCHEMBL31163190 0.74 LMNA (0.47) CYP1A2MAPTGAARECQLCYP2C19
SCHEMBL17703254 0.73 KMT2A (0.52) CYP1A2MAPTGAARECQLCYP2C19
SCHEMBL31719630 0.72 ALDH1A1 (0.43) TSHRALDH1A1KMT2ASMN1; SMN2TDP1
SCHEMBL31405498 0.71 LMNA (0.61) CYP1A2MAPTGAACYP2C19NPSR1
SCHEMBL4813243 0.70 CYP1A2 (0.59) CYP1A2MAPTGAACYP2C19HTT
SCHEMBL17703249 0.69 CYP1A2 (0.48) CYP1A2MAPTGAARECQLCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025033011-A1 FIVE-MEMBERED HETEROARYL COMPOUND AND AGRICULTURAL AND HORTICULTURAL BACTERICIDE 日本曹達株式会社 2025-02-13 WO disclosed