SCHEMBL31362989

SCHEMBL31362989

Cn1ncc(I)c1C(=O)OC(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRG2 P18507 4/20 0.35
GABRB3 P28472 4/20 0.35
GABRA5 P31644 4/20 0.35
GABRA1 P14867 3/20 0.35
GABRA3 P34903 3/20 0.35
GABRA2 P47869 3/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 2/20 0.34
GABRA6 Q16445 2/20 0.33
PKM P14618 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GABRA4 P48169 1/20 0.33
HTT P42858 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31362961 0.81 ALDH1A1 (0.35) GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL16177237 0.81 CNR2 (0.46) CYP1A2CYP2C19KMT2APKMLMNA
SCHEMBL21807935 0.80 CYP1A2 (0.46) CYP1A2CYP2C19KMT2ALMNAHPGD
SCHEMBL15897191 0.77 KMT2A (0.49) CYP1A2CYP2C19KMT2ALMNAHPGD
SCHEMBL2588985 0.74 KDM4E (0.37) CYP1A2CYP2C19KMT2AKDM4EALDH1A1
SCHEMBL20772872 0.73 GSK3B (0.39) KMT2AMEN1
SCHEMBL24806964 0.73 GABRA1 (0.33) GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL28646792 0.73 SLC22A12 (0.36) GABRG2GABRB3GABRA5GABRA1GABRA3
SCHEMBL16177346 0.73 ALDH1A1 (0.41) CYP1A2KMT2ALMNAHPGDKDM4E
SCHEMBL29153875 0.72 GABRA1 (0.34) GABRG2GABRB3GABRA5GABRA1GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025033011-A1 FIVE-MEMBERED HETEROARYL COMPOUND AND AGRICULTURAL AND HORTICULTURAL BACTERICIDE 日本曹達株式会社 2025-02-13 WO disclosed