SCHEMBL3136322

SCHEMBL3136322

COCNC(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.62
GAA P10253 1/20 0.61
SMN1; SMN2 Q16637 4/20 0.55
POLB P06746 2/20 0.55
LMNA P02545 1/20 0.55
TDP1 Q9NUW8 1/20 0.54
PRSS1 P07477 2/20 0.53
CTSG P08311 2/20 0.53
CTRB1 P17538 2/20 0.53
CMA1 P23946 2/20 0.53
TSHR P16473 1/20 0.52
ALDH1A1 P00352 3/20 0.52
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
NAAA Q02083 1/20 0.51
HDAC1 Q13547 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11350660 0.93 HPGD (0.59) HPGDGAASMN1; SMN2POLBLMNA
SCHEMBL13383872 0.90 ALDH1A1 (0.62) HPGDGAAPOLBLMNAALDH1A1
SCHEMBL4449880 0.89 RAB9A (0.60) HPGDSMN1; SMN2POLBLMNANPC1
SCHEMBL30996104 0.87 SMN1; SMN2 (0.64) HPGDGAASMN1; SMN2POLBLMNA
SCHEMBL8332440 0.82 GFER (0.59) HPGDGAASMN1; SMN2POLBLMNA
SCHEMBL364448 0.82 HPGD (0.87) HPGDGAASMN1; SMN2POLBLMNA
SCHEMBL3943418 0.81 GAA (0.57) HPGDGAASMN1; SMN2POLBLMNA
SCHEMBL7758887 0.81 GAA (0.57) HPGDGAASMN1; SMN2POLBLMNA
SCHEMBL3184986 0.81 GAA (0.57) HPGDGAASMN1; SMN2POLBLMNA
SCHEMBL4241470 0.81 CYP1A2 (0.60) GAASMN1; SMN2LMNATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9124569-A None JP disclosed
CN-118272274-B Lactic acid bacteria starter and application thereof in preparation of blueberry corn peptide fermentation liquor 齐齐哈尔大学 2024-08-09 CN disclosed
CN-118272274-A Lactic acid bacteria starter and application thereof in preparation of blueberry corn peptide fermentation liquor 齐齐哈尔大学 2024-07-02 CN disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
US-10752640-B2 Compounds active towards bromodomains NUEVOLUTION A/S (DK) 2020-08-25 US disclosed
EP-3661941-A1 THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS Merck Patent GmbH (DE) 2020-06-10 EP disclosed
WO-2020011147-A1 RORγ ANTAGONIST AND APPLICATION THEREOF IN MEDICINE SUNSHINE LAKE PHARMA CO., LTD. (CN) 2020-01-16 WO disclosed
WO-2019025099-A1 THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS MERCK PATENT GMBH (DE) 2019-02-07 WO disclosed
US-20170349607-A1 COMPOUNDS ACTIVE TOWARDS BROMODOMAINS NUEVOLUTION A/S (DK) 2017-12-07 US disclosed
US-9409917-B2 Heterocyclic amide derivatives as P2X7 receptor antagonists ACTELION PHARMACEUTICALS LTD. (CH) 2016-08-09 US disclosed
US-5723165-A ARTIFICIAL SWEETENERS AJINOMOTO CO., INC. (JP) 1998-03-03 US disclosed
EP-0776883-A1 Adduct salts of substituted benzylamine and a process for optically resolving them Ajinomoto Co., Inc. (JP) 1997-06-04 EP disclosed
JP-H09124569-A PRODUCTION OF BENZAMIDE DERIVATIVE DAINIPPON INK & CHEM INC 1997-05-13 JP disclosed
EP-0719789-A1 Process of producing alpha-L-aspartyldipeptide amide derivatives Ajinomoto Co., Ltd. (JP) 1996-07-03 EP disclosed
EP-0691346-A1 Novel aspartyldipeptide derivatives and sweetener Ajinomoto Co., Inc. (JP) 1996-01-10 EP disclosed
US-4678611-A Novel dyestuff intermediates and use thereof for the manufacture of novel azo dyes CIBA-GEIGY CORPORATION (US) 1987-07-07 US disclosed
US-4360460-A Novel azo dyes having a 4-sulfo-5-aminomethyl naphthalene coupling moiety CIBA-GEIGY AG (CH) 1982-11-23 US disclosed
US-4288363-A Novel azo dyes having 2-amino-5-aminomethyl-7-sulfo naphthalene coupling moiety CIBA-GEIGY CORPORATION (US) 1981-09-08 US disclosed
US-4126609-A AZO DYESTUFF WITH A FIBER-REACTIVE GROUP ATTACHED TO A NAPHTHALENE SULPHONIC ACID COMPONENT BAYER AKTIENGESELLSCHAFT (DE) 1978-11-21 US disclosed
US-4049704-A AZO REACTIVE DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170349607-A1 COMPOUNDS ACTIVE TOWARDS BROMODOMAINS BRD4, BRD3, BRDT HPGD 2141/4885GAA 1396/4885SMN1; SMN2 2459/4885
US-10752640-B2 Compounds active towards bromodomains BRD4, BRD3, BRDT HPGD 2141/4885GAA 1396/4885SMN1; SMN2 2459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.