SCHEMBL31363601

SCHEMBL31363601

Nc1cc(I)cc2c1ccn2CC(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ASH1L Q9NR48 1/20 0.39
MAPT P10636 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31364109 0.81 ASH1L (0.39) ASH1L
SCHEMBL31363125 0.78 ASH1L (0.37) ASH1L
SCHEMBL31363399 0.76 HTR6 (0.36) ASH1L
SCHEMBL14977330 0.76 ASH1L (0.41) ASH1L
SCHEMBL29811286 0.76 ASH1L (0.41) ASH1L
SCHEMBL31363362 0.75 SLC2A1 (0.44)
SCHEMBL31363716 0.74 GRIN2B (0.38) MAPT
SCHEMBL28258100 0.69 ASH1L (0.41) ASH1L
SCHEMBL31363228 0.69 EHMT2 (0.36)
SCHEMBL20939510 0.67 MAP3K14 (0.37) ASH1L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059074-A1 BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION PMV PHARMACEUTICALS, INC. (US) 2025-03-20 WO disclosed