Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569138 | 1.00 | LMNA (0.44) | LMNAMAPTCA1CA2CA4 | |
| SCHEMBL4442111 | 0.78 | LMNA (0.39) | LMNAMAPT | |
| SCHEMBL15740737 | 0.78 | LMNA (0.39) | LMNAMAPT | |
| SCHEMBL6018336 | 0.78 | LMNA (0.39) | LMNAMAPT | |
| SCHEMBL16371027 | 0.75 | LMNA (0.37) | LMNAMAPT | |
| SCHEMBL17785721 | 0.73 | LMNA (0.36) | LMNAMAPT | |
| SCHEMBL13035655 | 0.73 | ATM (0.38) | LMNAMAPTL3MBTL1 | |
| SCHEMBL1476498 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL5356449 | 0.70 | LMNA (0.41) | LMNAMAPTCA1CA2CA4 | |
| SCHEMBL7997715 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |