Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045319 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL31363678 | 0.75 | LMNA (0.44) | LMNAMAPT | |
| SCHEMBL2569138 | 0.75 | LMNA (0.44) | LMNAMAPT | |
| SCHEMBL13389307 | 0.75 | BRD4 (0.31) | — | |
| SCHEMBL6018336 | 0.73 | LMNA (0.39) | LMNAMAPT | |
| SCHEMBL10202863 | 0.73 | — | — | |
| SCHEMBL4442111 | 0.73 | LMNA (0.39) | LMNAMAPT | |
| SCHEMBL656014 | 0.69 | DDB1 (0.44) | MAPT | |
| SCHEMBL17785721 | 0.69 | LMNA (0.36) | LMNAMAPT | |
| SCHEMBL6849414 | 0.68 | ESR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116848114-A | Tricyclic derivatives useful as PARP7 inhibitors | 北京加科思新药研发有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-109053742-A | New tricyclic compound | ABBVIE 公司 | 2018-12-21 | — | — | CN | disclosed |
| WO-2015006689-A1 | TREATMENT AND DIAGNOSIS OF CANCER AND PRECANCEROUS CONDITIONS USING PDE10A INHIBITORS AND METHODS TO MEASURE PDE10A EXPRESSION | UNIVERSITY OF SOUTH ALABAMA (US) | 2015-01-15 | — | — | WO | disclosed |