Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31363399 | 0.85 | HTR6 (0.36) | ASH1LHTR6CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL14981533 | 0.80 | TDP1 (0.44) | ASH1LALDH1A1GAACYP3A4CYP1A2 | |
| SCHEMBL26914717 | 0.79 | SOS1 (0.41) | HTR6ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL31364109 | 0.77 | ASH1L (0.39) | ASH1L | |
| SCHEMBL31363930 | 0.75 | ASH1L (0.37) | ASH1LMEN1KMT2AIDO1 | |
| SCHEMBL26683500 | 0.71 | ERN1 (0.38) | S100A4TRPV1HTR6CTSBERN1 | |
| SCHEMBL31363868 | 0.71 | NR4A2 (0.41) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL21636616 | 0.69 | ASH1L (0.38) | ASH1L | |
| SCHEMBL18491500 | 0.69 | AR (0.49) | CYP1A2 | |
| SCHEMBL25340072 | 0.68 | MAPT (0.37) | HTR6ERN1ALDH1A1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |