Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.37 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31363868 | 0.84 | NR4A2 (0.41) | HTR3AMEN1KMT2A | |
| SCHEMBL19260954 | 0.78 | KDM4E (0.43) | ASH1LCYP19A1KDM4ENR4A1HTR3A | |
| SCHEMBL31364109 | 0.77 | ASH1L (0.39) | ASH1L | |
| SCHEMBL31363686 | 0.75 | ASH1L (0.34) | ASH1LIDO1MEN1KMT2A | |
| SCHEMBL20604814 | 0.73 | PTPN1 (0.44) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E | |
| SCHEMBL16899455 | 0.72 | NOTUM (0.33) | ASH1LEPRS1CYP19A1RHEBMYC | |
| SCHEMBL31364001 | 0.72 | BACE1 (0.37) | RXFP1 | |
| SCHEMBL2654320 | 0.71 | HTR3A (0.47) | KDM4CHTR3AIDO1MEN1KMT2A | |
| SCHEMBL30838224 | 0.71 | CNR1 (0.36) | AKR1C3AKR1C2AKR1C1AKR1C4KDM4E | |
| SCHEMBL28489856 | 0.70 | CYP19A1 (0.45) | CYP19A1KDM4EMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |