Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30870921 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL23144748 | 0.88 | TOP2B (0.48) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL25325370 | 0.79 | TOP2B (0.40) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL30099039 | 0.78 | LRRK2 (0.42) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL25033550 | 0.78 | LRRK2 (0.42) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL23144768 | 0.77 | CA12 (0.40) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL29812039 | 0.77 | CA12 (0.49) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL23143891 | 0.77 | CA12 (0.49) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL23144126 | 0.77 | CA12 (0.45) | SMN1; SMN2CA12CA1CA2CA9 | |
| SCHEMBL23156236 | 0.77 | LRRK2 (0.44) | SMN1; SMN2ALDH1A1LMNATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |