SCHEMBL31363983

SCHEMBL31363983

CC(C)n1ccc2c(N)cc(I)cc21

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31363362 0.76 SLC2A1 (0.44)
SCHEMBL2595998 0.74 EZH2 (0.37)
SCHEMBL26116168 0.74 HCAR3 (0.41) MAPT
SCHEMBL13773249 0.73 CYP3A4 (0.39)
SCHEMBL26119676 0.71 KDM4E (0.44) MAPT
SCHEMBL26622838 0.70 NFATC1 (0.41)
SCHEMBL13864203 0.67 EZH2 (0.38)
SCHEMBL31363996 0.67 POLB (0.36)
SCHEMBL31363601 0.66 ASH1L (0.39) MAPT
SCHEMBL21244778 0.66 BRD4 (0.36) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059074-A1 BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION PMV PHARMACEUTICALS, INC. (US) 2025-03-20 WO disclosed