SCHEMBL31364097

SCHEMBL31364097

Clc1cccc2c(C3CCCCC3)nccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
TDO2 P48775 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
AURKA O14965 3/20 0.38
JAK2 O60674 3/20 0.38
PRKCA P17252 3/20 0.38
JAK1 P23458 3/20 0.38
TYK2 P29597 3/20 0.38
KDR P35968 3/20 0.38
FLT3 P36888 3/20 0.38
NR4A2 P43354 2/20 0.37
GLA P06280 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ACHE P22303 1/20 0.35
GRM2 Q14416 1/20 0.35
CYP17A1 P05093 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11254155 1.00 OPRL1 (0.42) OPRL1CYP1A2CYP2A6TDO2TDP1
SCHEMBL28459553 0.81 PLAU (0.42) OPRL1TDO2TDP1L3MBTL1AURKA
SCHEMBL11260207 0.80 TDP1 (0.35) OPRL1TDO2TDP1L3MBTL1AURKA
SCHEMBL31364014 0.80 TDP1 (0.43) OPRL1CYP1A2CYP2A6TDP1L3MBTL1
SCHEMBL11261376 0.78 KDM4E (0.41) OPRL1TDO2TDP1L3MBTL1AURKA
SCHEMBL31364004 0.78 TDP1 (0.49) TDP1L3MBTL1AURKAJAK2PRKCA
SCHEMBL7709519 0.78 OPRL1 (0.61) OPRL1GRM2CYP11B2HSD11B1
SCHEMBL11251670 0.77 ELANE (0.40) TDP1L3MBTL1AURKAJAK2PRKCA
SCHEMBL31364183 0.77 PLAU (0.46) HTT
SCHEMBL31364113 0.75 TDP1 (0.50) CYP1A2TDP1L3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638622-A Photocatalytic alkane C (sp)3) Method for activating H bond and constructing C-C bond with aza arene 中国科学院理化技术研究所 2025-03-18 CN disclosed