SCHEMBL31364183

SCHEMBL31364183

COc1cccc2c(C3CCCCC3)nccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.46
CCNT1 O60563 1/20 0.40
CDK9 P50750 1/20 0.40
JUND P17535 1/20 0.40
FOSB P53539 1/20 0.40
ABCB1 P08183 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
HTR1A P08908 1/20 0.38
ADRA1D P25100 1/20 0.38
ADRA1A P35348 1/20 0.38
ADRA1B P35368 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PDE10A Q9Y233 2/20 0.37
GRM1 Q13255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
ACVR2A P27037 1/20 0.37
TGFBR2 P37173 1/20 0.37
ADORA2A P29274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31364111 0.80 PLAU (0.51) PLAUHTR1AALDH1A1MAPT
SCHEMBL31364097 0.77 OPRL1 (0.42) HTT
SCHEMBL11254155 0.77 OPRL1 (0.42) HTT
SCHEMBL28459553 0.77 PLAU (0.42) PLAU
SCHEMBL7854624 0.77 PDGFRB (0.47) PDE10AALDH1A1MAPTTNFKDM4E
SCHEMBL24715878 0.75 HTR1A (0.50) CCNT1CDK9ABCB1HTR1AADRA1D
SCHEMBL7853663 0.75 PDGFRB (0.48) PDE10AALDH1A1MAPTTNFKDM4E
SCHEMBL11261376 0.75 KDM4E (0.41) CDK9HTTMAPTKDM4ETSHR
SCHEMBL31364004 0.75 TDP1 (0.49) CDK9ALDH1A1MAPTADORA2ATNF
SCHEMBL25256999 0.73 HTR1A (0.51) HTR1AADRA1DADRA1AADRA1BADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638622-A Photocatalytic alkane C (sp)3) Method for activating H bond and constructing C-C bond with aza arene 中国科学院理化技术研究所 2025-03-18 CN disclosed