SCHEMBL31364598

SCHEMBL31364598

CC(=O)c1ccc2c(C(C)=O)c(O)ccc2c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.59
ALDH1A1 P00352 2/20 0.59
MAPT P10636 2/20 0.59
LCK P06239 2/20 0.49
CYP2A6 P11509 1/20 0.49
PKM P14618 1/20 0.47
PTPN1 P18031 1/20 0.44
THRB P10828 1/20 0.44
CA9 Q16790 1/20 0.44
HTT P42858 1/20 0.42
POLB P06746 1/20 0.41
HSD17B1 P14061 1/20 0.40
CA2 P00918 1/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
CYP3A4 P08684 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28755402 0.84 MAPT (0.61) HPGDALDH1A1MAPTLCKCYP2A6
SCHEMBL15917911 0.84 PTPN1 (0.46) HPGDALDH1A1MAPTPTPN1THRB
SCHEMBL28795552 0.81 ALDH1A1 (0.57) HPGDALDH1A1MAPTLCKCYP2A6
SCHEMBL23640322 0.81 PTPN1 (0.43) HPGDALDH1A1MAPTLCKPTPN1
SCHEMBL23640511 0.81 ERN1 (0.54) HPGDALDH1A1MAPTPTPN1THRB
SCHEMBL23640287 0.78 CYP3A4 (0.56) HPGDALDH1A1MAPTCYP2A6CYP3A4
SCHEMBL22750623 0.78 ERN1 (0.62) HPGDALDH1A1MAPT
SCHEMBL31364601 0.78 ALDH1A1 (0.54) HPGDALDH1A1MAPTLCKCYP2A6
SCHEMBL10970308 0.76 ALDH1A1 (0.66) HPGDALDH1A1MAPTCYP2A6PKM
SCHEMBL3914003 0.76 KDM4E (0.53) HPGDALDH1A1MAPTLCKPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119470678-A Method for separating and measuring key intermediate and related impurities of non-steroidal anti-inflammatory drug by HPLC (high Performance liquid chromatography) 上海博悦生物科技有限公司 2025-02-18 CN claimed
CN-119470678-A Method for separating and measuring key intermediate and related impurities of non-steroidal anti-inflammatory drug by HPLC (high Performance liquid chromatography) 上海博悦生物科技有限公司 2025-02-18 CN disclosed