Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27681040 | 0.84 | ALDH1A1 (0.76) | POLBALDH1A1KDM4EPTPN11KMT2A | |
| SCHEMBL6868441 | 0.79 | POLB (0.54) | POLBALDH1A1KDM4EPTPN11KMT2A | |
| SCHEMBL27586071 | 0.79 | KDM4E (0.54) | POLBALDH1A1KDM4EPTPN11KMT2A | |
| SCHEMBL10413764 | 0.76 | KDM4E (0.51) | POLBALDH1A1KDM4EKMT2AMAPK1 | |
| SCHEMBL605729 | 0.76 | POLB (1.00) | POLBALDH1A1KDM4EPTPN11KMT2A | |
| SCHEMBL6865981 | 0.75 | CYP1A2 (0.49) | POLBALDH1A1PTPN11MAPK1TSHR | |
| SCHEMBL1013949 | 0.75 | POLB (0.59) | POLBALDH1A1KDM4EPTPN11KMT2A | |
| SCHEMBL8085653 | 0.75 | POLB (0.59) | POLBALDH1A1KDM4EPTPN11KMT2A | |
| SCHEMBL27533652 | 0.75 | POLB (0.59) | POLBALDH1A1KDM4EPTPN11KMT2A | |
| SCHEMBL245978 | 0.75 | PTPN11 (0.69) | POLBALDH1A1KDM4EPTPN11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025021148-A1 | WRN INHIBITOR, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 贝达药业股份有限公司 | 2025-01-30 | — | — | WO | disclosed |