SCHEMBL1013949

SCHEMBL1013949

Cc1nc(N2CCOCC2)ncc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.57
HSD11B1 P28845 1/20 0.55
ALDH1A1 P00352 4/20 0.54
KDM4E B2RXH2 3/20 0.54
PTPN11 Q06124 1/20 0.52
CYP1A2 P05177 2/20 0.50
HSD17B10 Q99714 2/20 0.50
USP2 O75604 1/20 0.50
PIK3CA P42336 2/20 0.47
PIK3CD O00329 1/20 0.47
PIK3CB P42338 1/20 0.47
DGAT1 O75907 1/20 0.46
CYP3A4 P08684 1/20 0.46
KMT2A Q03164 1/20 0.46
PIK3R1 P27986 1/20 0.46
MTOR P42345 1/20 0.46
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
RBP4 P02753 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32671622 0.86 POLB (0.75) POLBSMN1; SMN2ALDH1A1PTPN11MAPT
SCHEMBL32671619 0.86 HSD11B1 (0.55) POLBSMN1; SMN2HSD11B1ALDH1A1KDM4E
SCHEMBL30331571 0.85 POLB (0.78) POLBSMN1; SMN2ALDH1A1PTPN11MAPT
SCHEMBL1014805 0.85 ALDH1A1 (0.55) POLBSMN1; SMN2HSD11B1ALDH1A1KDM4E
SCHEMBL32671634 0.84 POLB (0.58) POLBSMN1; SMN2ALDH1A1CYP1A2HSD17B10
SCHEMBL8085653 0.82 POLB (0.59) POLBSMN1; SMN2HSD11B1ALDH1A1KDM4E
SCHEMBL245978 0.82 PTPN11 (0.69) POLBALDH1A1KDM4EPTPN11HSD17B10
SCHEMBL27533652 0.82 POLB (0.59) POLBSMN1; SMN2HSD11B1ALDH1A1KDM4E
SCHEMBL1015076 0.82 HSD11B1 (0.57) POLBSMN1; SMN2HSD11B1ALDH1A1KDM4E
SCHEMBL18186151 0.81 POLB (0.50) POLBSMN1; SMN2HSD11B1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692067-A1 SALTS OF N-SUBSTITUTED 2-AMINO-4-METHYLPYRIMIDINE-5-YL-CARBOXYLIC ACIDS AS GROWTH STIMULATORS FOR PLANTS AND FUNGI OCC Management GmbH (CH) 2026-02-11 EP claimed
EP-4692067-A1 SALTS OF N-SUBSTITUTED 2-AMINO-4-METHYLPYRIMIDINE-5-YL-CARBOXYLIC ACIDS AS GROWTH STIMULATORS FOR PLANTS AND FUNGI OCC Management GmbH (CH) 2026-02-11 EP disclosed
US-10968223-B2 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors PROXIMAGEN, LLC (US) 2021-04-06 US disclosed
US-10968223-B2 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors PROXIMAGEN, LLC (US) 2021-04-06 US disclosed
US-20200347059-A1 IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS PROXIMAGEN, LLC (US) 2020-11-05 US disclosed
US-20200347059-A1 IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS PROXIMAGEN, LLC (US) 2020-11-05 US disclosed
US-10766897-B2 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors PROXIMAGEN, LLC (US) 2020-09-08 US disclosed
US-10766897-B2 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors PROXIMAGEN, LLC (US) 2020-09-08 US disclosed
US-10428066-B2 Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors PROXIMAGEN, LLC (US) 2019-10-01 US disclosed
US-10428066-B2 Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors PROXIMAGEN, LLC (US) 2019-10-01 US disclosed
US-20150258101-A1 NEW COMPOUNDS PROXIMAGEN LIMITED (GB) 2015-09-17 US disclosed
US-20150258101-A1 NEW COMPOUNDS PROXIMAGEN LIMITED (GB) 2015-09-17 US disclosed
CN-102066335-A Substituted pyrimidin-5-carboxamides 281 ASTRAZENECA AB 2011-05-18 CN disclosed
EP-2271629-A1 SUBSTITUTED PYRIMIDIN-5-CARBOXAMIDES 281 AstraZeneca AB (SE) 2011-01-12 EP disclosed
WO-2009130496-A1 SUBSTITUTED PYRIMIDIN-5-CARBOXAMIDES 281 ASTRAZENECA AB (SE) 2009-10-29 WO disclosed
WO-2009130496-A1 SUBSTITUTED PYRIMIDIN-5-CARBOXAMIDES 281 ASTRAZENECA AB (SE) 2009-10-29 WO disclosed
US-20090264401-A1 SUBSTITUTED PYRIMIDIN-5-CARBOXAMIDES 281 ASTRAZENECA AB (SE) 2009-10-22 US disclosed
US-20090264401-A1 SUBSTITUTED PYRIMIDIN-5-CARBOXAMIDES 281 ASTRAZENECA AB (SE) 2009-10-22 US disclosed
US-20090264401-A1 SUBSTITUTED PYRIMIDIN-5-CARBOXAMIDES 281 ASTRAZENECA AB (SE) 2009-10-22 US disclosed
CN-101023063-A Azine-carboxamides as anti-cancer agents ASTRAZENECA AB (SE) 2007-08-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264401-A1 SUBSTITUTED PYRIMIDIN-5-CARBOXAMIDES 281 CYP2S1, HSD11B1, HSD3B1 POLB 2006/4885SMN1; SMN2 2203/4885HSD11B1 2/4885
US-10766897-B2 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors PNPO, SSB, XDH POLB 759/4885SMN1; SMN2 895/4885HSD11B1 3432/4885
US-10428066-B2 Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors PNPO, SSB, XDH POLB 759/4885SMN1; SMN2 895/4885HSD11B1 3432/4885
US-10968223-B2 Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors PNPO, PPOX, SCO2 POLB 1538/4885SMN1; SMN2 762/4885HSD11B1 2708/4885
US-20200347059-A1 IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS PNPO, PPOX, SCO2 POLB 1538/4885SMN1; SMN2 762/4885HSD11B1 2708/4885
US-20150258101-A1 NEW COMPOUNDS AOX1, QSOX1, MAOB POLB 557/4885SMN1; SMN2 2162/4885HSD11B1 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.