Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22139940 | 1.00 | LMNA (0.38) | LMNAHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL22119996 | 0.82 | LMNA (0.39) | LMNAHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL22139945 | 0.82 | CYP1A2 (0.47) | LMNACCR4L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL20840567 | 0.81 | KDM4E (0.34) | TDP1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22120146 | 0.80 | GAA (0.37) | CCR4GAACA2CA4PKM | |
| SCHEMBL8706883 | 0.79 | GAA (0.51) | LMNAHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL8707599 | 0.78 | TSHR (0.39) | LMNAHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL10257661 | 0.77 | GAA (0.36) | LMNAHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL22120070 | 0.73 | CYP1A2 (0.38) | CCR4GAAMEN1KMT2AKDM4E | |
| SCHEMBL29844244 | 0.73 | PDK2 (0.32) | LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026081-B | Pyridone derivatives as selective cytotoxic agents against HIV-infected cells | 默沙东有限责任公司 | 2025-02-11 | — | — | CN | disclosed |