SCHEMBL31366263

SCHEMBL31366263

Cc1ccc(S(=O)(=O)n2cc(CCCO)c3cc(C)ccc32)cc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 12/20 0.56
PPARG P37231 5/20 0.51
PPARD Q03181 5/20 0.51
PPARA Q07869 5/20 0.51
ALK Q9UM73 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.47
KDM4E B2RXH2 1/20 0.45
UBE2N P61088 1/20 0.45
HTR1A P08908 1/20 0.44
DRD2 P14416 1/20 0.44
HTR1D P28221 1/20 0.44
HTR1B P28222 1/20 0.44
HTR1E P28566 1/20 0.44
HTR1F P30939 1/20 0.44
HTR7 P34969 1/20 0.44
DRD3 P35462 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31366266 0.91 HTR6 (0.53) HTR6PPARGPPARDPPARAALK
SCHEMBL31366254 0.88 HTR6 (0.73) HTR6ALKL3MBTL1KDM4EUBE2N
SCHEMBL8261023 0.84 HTR6 (0.59) HTR6PPARGPPARDPPARAALK
SCHEMBL28437836 0.80 HTR6 (0.53) HTR6PPARGPPARDPPARAALK
SCHEMBL13210118 0.79 HTR6 (0.61) HTR6PPARGPPARDPPARAALK
SCHEMBL28442103 0.79 HTR6 (0.53) HTR6PPARGPPARDPPARAALK
SCHEMBL28442164 0.79 HTR6 (0.53) HTR6PPARGPPARDPPARAALK
SCHEMBL5091186 0.79 HTR6 (0.58) HTR6PPARGPPARDPPARAALK
SCHEMBL3033157 0.78 PPARG (0.65) HTR6PPARGPPARDPPARAHTR1A
SCHEMBL5355639 0.78 PPARG (0.72) HTR6PPARGPPARDPPARAHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431386-A Synthesis method of 2'- (trifluoromethyl) -4, 5-dihydro-spiro [ furan-2, 3' -indoline ] derivative 西北师范大学 2025-02-14 CN disclosed