Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16570039 | 0.96 | L3MBTL1 (0.39) | TP53L3MBTL1KDM4ETLR8ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL31366375 | 0.92 | KMT2A (0.36) | TP53L3MBTL1KDM4ETLR8ALDH1A1 | |
| Sulfuric Acid SCHEMBL28489606 | 0.91 | L3MBTL1 (0.40) | L3MBTL1KDM4EALDH1A1KMT2ACYP2D6 | |
| SCHEMBL27975187 | 0.90 | L3MBTL1 (0.40) | L3MBTL1KDM4EALDH1A1KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL29179965 | 0.88 | L3MBTL1 (0.40) | L3MBTL1KDM4EALDH1A1KMT2ACYP2D6 | |
| Sulfuric Acid SCHEMBL28423116 | 0.85 | L3MBTL1 (0.41) | L3MBTL1KDM4EALDH1A1KMT2ACYP2D6 | |
| Sulfuric Acid SCHEMBL17232934 | 0.84 | L3MBTL1 (0.37) | L3MBTL1KDM4EALDH1A1KMT2ACYP2D6 | |
| SCHEMBL27998888 | 0.83 | L3MBTL1 (0.42) | L3MBTL1KDM4EALDH1A1KMT2ACYP2D6 | |
| Trifluoromethanesulfonic Acid SCHEMBL28357591 | 0.82 | KMT2A (0.38) | L3MBTL1KDM4EALDH1A1KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL29043668 | 0.82 | L3MBTL1 (0.41) | L3MBTL1KDM4EALDH1A1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114877069-B | Metal-coated gasket filled with modified ceramic fibers and preparation method thereof | 慈溪埃弗龙密封件有限公司 | 2025-01-28 | — | — | CN | disclosed |