Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26979907 | 0.89 | DGAT1 (0.39) | MAPTDGAT1P2RX7CDC7CDK2 | |
| SCHEMBL1258087 | 0.81 | CDK4 (0.49) | HTR2AHTR2C | |
| SCHEMBL29492554 | 0.81 | CDK4 (0.49) | HTR2AHTR2C | |
| SCHEMBL30630186 | 0.79 | GRM2 (0.40) | MAPTDGAT1CDK2HTR2AHTR2C | |
| SCHEMBL26728337 | 0.77 | HTR2A (0.48) | DGAT1P2RX7HTR2AHTR2C | |
| SCHEMBL29746608 | 0.77 | MAPT (0.41) | MAPTDGAT1 | |
| SCHEMBL24805178 | 0.77 | DGAT1 (0.39) | MAPTDGAT1CDC7CDK2HTR2A | |
| SCHEMBL8252347 | 0.76 | HTR7 (0.42) | DGAT1HTR2AHTR2C | |
| SCHEMBL22778051 | 0.76 | DGAT1 (0.36) | DGAT1HTR2AHTR2C | |
| SCHEMBL30475587 | 0.76 | HTR7 (0.42) | DGAT1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431358-A | Pyrrolopyridines, compositions thereof and their use in medicine | 中国科学院上海药物研究所 | 2025-02-14 | — | — | CN | disclosed |