Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | CCKBR | P32239 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25409104 | 1.00 | OPRK1 (0.54) | OPRK1LMNAPDE3ACHRM1PDE4D | |
| SCHEMBL25413379 | 1.00 | OPRK1 (0.54) | OPRK1LMNAPDE3ACHRM1PDE4D | |
| SCHEMBL25408171 | 0.93 | OPRK1 (0.55) | OPRK1LMNAPDE3ACHRM1PDE4D | |
| SCHEMBL31366514 | 0.93 | OPRK1 (0.55) | OPRK1LMNAPDE3ACHRM1PDE4D | |
| SCHEMBL25410836 | 0.93 | OPRK1 (0.55) | OPRK1LMNAPDE3ACHRM1PDE4D | |
| SCHEMBL31366595 | 0.90 | OPRK1 (0.53) | OPRK1LMNAPDE3ACHRM1PDE4D | |
| SCHEMBL25409665 | 0.90 | OPRK1 (0.53) | OPRK1LMNAPDE3ACHRM1PDE4D | |
| SCHEMBL25409659 | 0.90 | OPRK1 (0.53) | OPRK1LMNAPDE3ACHRM1PDE4D | |
| SCHEMBL31366516 | 0.89 | CCKBR (0.59) | OPRK1LMNAPDE3ACHRM1PDE4D | |
| SCHEMBL31630018 | 0.89 | CCKBR (0.59) | OPRK1LMNAPDE3ACHRM1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119072467-A | Novel diazapine compounds targeting yellow fever virus non-structural 4B (NS 4B) protein and methods of use thereof | 巴鲁克斯布伦博格研究所 | 2024-12-03 | — | — | CN | disclosed |