Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11480904 | 0.89 | RARB (0.39) | PPARARARBPPARGRORCESR2 | |
| SCHEMBL16941050 | 0.85 | PTGS1 (0.46) | PTGS1PTGS2PDE3BPDE3ANMT1 | |
| SCHEMBL12603798 | 0.84 | PTGS1 (0.44) | PTGS1PTGS2PDE3BPDE3ANMT1 | |
| SCHEMBL12496670 | 0.82 | LOXL2 (0.52) | PTGS1PTGS2PDE3BPDE3AMAOB | |
| SCHEMBL12050458 | 0.81 | ESR2 (0.53) | PPARARARBOXTRAVPR1APPARG | |
| SCHEMBL31366931 | 0.81 | ESR2 (0.53) | PPARARARBOXTRAVPR1APPARG | |
| SCHEMBL16941081 | 0.81 | RARB (0.50) | PTGS1PTGS2PDE3BPDE3APPARA | |
| SCHEMBL3748937 | 0.78 | PDE3B (0.46) | PTGS2PDE3BPDE3ANMT1GRIN1 | |
| SCHEMBL23394399 | 0.78 | PTPN5 (0.43) | PTGS1PTGS2PPARAGRIN1GRIN2B | |
| SCHEMBL22621148 | 0.78 | RARB (0.51) | PTGS1PTGS2PDE3BPDE3ARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119487006-A | Amide compounds as PGE2 receptor antagonists | 广东新契生物医药科技有限公司 | 2025-02-18 | — | — | CN | disclosed |