Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12050458 | 1.00 | ESR2 (0.53) | ESR2PPARGPPARATRPA1ALDH1A1 | |
| Formic Acid SCHEMBL28479997 | 0.90 | ESR2 (0.49) | ESR2PPARGPPARAMEN1LMNA | |
| SCHEMBL11480904 | 0.88 | RARB (0.39) | ESR2PPARGPPARATRPA1ALDH1A1 | |
| SCHEMBL15413958 | 0.82 | ESR2 (0.60) | ESR2PPARGPPARAALDH1A1TSHR | |
| SCHEMBL10520096 | 0.82 | ESR2 (0.55) | ESR2PPARGPPARAALDH1A1CSNK2A1 | |
| SCHEMBL21415408 | 0.82 | ESR2 (0.47) | ESR2PPARGPPARAHTR7RARB | |
| SCHEMBL1373277 | 0.82 | ALDH1A1 (0.48) | ESR2TRPA1ALDH1A1TSHRCSNK2A1 | |
| SCHEMBL31366924 | 0.81 | PTGS1 (0.43) | ESR2PPARGPPARARARBOXTR | |
| SCHEMBL24093211 | 0.81 | ESR2 (0.53) | ESR2PPARGPPARACSNK2A1MEN1 | |
| SCHEMBL2572842 | 0.81 | CSNK2A1 (0.62) | ESR2PPARGPPARACSNK2A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122070130-A | S1PR4 modulator compounds for myopathy treatment and uses thereof | 生元泽通(上海)医药有限公司 | 2026-05-19 | — | — | CN | disclosed |
| CN-122029146-A | S1PR4 modulator compounds for the treatment of autoimmune diseases and uses thereof | 生元泽通(上海)医药有限公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025077707-A1 | S1PR4 REGULATOR COMPOUND FOR AUTOIMMUNE DISEASE TREATMENT AND APPLICATION THEREOF | 华东师范大学 | 2025-04-17 | — | — | WO | disclosed |
| WO-2025077706-A1 | S1PR4 REGULATOR COMPOUND FOR MUSCLE DISEASE TREATMENT AND APPLICATION THEREOF | 华东师范大学 | 2025-04-17 | — | — | WO | disclosed |
| CN-119775186-A | S1PR4 modulator compounds for myopathy treatment and uses thereof | 华东师范大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119775185-A | S1PR4 modulator compounds for the treatment of autoimmune diseases and uses thereof | 华东师范大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119487006-A | Amide compounds as PGE2 receptor antagonists | 广东新契生物医药科技有限公司 | 2025-02-18 | — | — | CN | disclosed |