Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 2/20 | 0.44 |
| ▸ | XIAP | P98170 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186545 | 0.80 | PARP1 (0.68) | POLBPARP1HDAC8HDAC6KMT2A | |
| SCHEMBL29503529 | 0.80 | PARP1 (0.68) | POLBPARP1HDAC8HDAC6KMT2A | |
| SCHEMBL3140072 | 0.80 | POLB (0.62) | POLBPARP1HDAC8HDAC6KMT2A | |
| SCHEMBL31367009 | 0.79 | ALDH1A1 (0.58) | KMT2AHPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3132232 | 0.79 | POLB (0.60) | POLBPARP1HDAC8HDAC6KMT2A | |
| SCHEMBL15264066 | 0.78 | PARP1 (0.65) | POLBPARP1HDAC8HDAC6KMT2A | |
| SCHEMBL29738647 | 0.78 | POLB (0.69) | POLBPARP1HDAC8HDAC6KMT2A | |
| SCHEMBL822041 | 0.77 | PARP1 (0.63) | POLBPARP1HDAC8HDAC6KMT2A | |
| SCHEMBL21636267 | 0.76 | POLB (0.62) | POLBPARP1HDAC8HDAC6KMT2A | |
| SCHEMBL29530873 | 0.76 | POLB (0.72) | POLBPARP1HDAC8HDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116143689-B | Synthesis method of 2,3,5, 6-tetra-substituted pyridine compound | 重庆医科大学 | 2025-01-28 | — | — | CN | disclosed |