SCHEMBL31367014

SCHEMBL31367014

COC(=O)C1CC(=CN(C)C)C(=O)N1C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.43
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PTPN1 P18031 1/20 0.34
NR1H2 P55055 2/20 0.33
NR1H3 Q13133 1/20 0.33
MMP2 P08253 1/20 0.33
ANPEP P15144 1/20 0.33
KLK7 P49862 5/20 0.32
PDE4B Q07343 1/20 0.32
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
KLK5 Q9Y337 4/20 0.31
PRSS1 P07477 2/20 0.31
PRSS2 P07478 2/20 0.31
PRSS3 P35030 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13520372 1.00 P2RX7 (0.43) P2RX7GAAMAPTNPSR1PTPN1
SCHEMBL31739666 1.00 P2RX7 (0.43) P2RX7GAAMAPTNPSR1PTPN1
SCHEMBL31739904 1.00 P2RX7 (0.43) P2RX7GAAMAPTNPSR1PTPN1
SCHEMBL2601625 1.00 P2RX7 (0.43) P2RX7GAAMAPTNPSR1PTPN1
SCHEMBL25525219 1.00 P2RX7 (0.43) P2RX7GAAMAPTNPSR1PTPN1
SCHEMBL28926788 1.00 P2RX7 (0.43) P2RX7GAAMAPTNPSR1PTPN1
SCHEMBL27017254 0.92 P2RX7 (0.35) P2RX7NR1H2KLK7DDB1CRBN
SCHEMBL25415023 0.88 NFKB1 (0.39) P2RX7GAAMAPTKLK7NFKB1
SCHEMBL8224217 0.88 NFKB1 (0.39) P2RX7GAAMAPTKLK7NFKB1
SCHEMBL14453008 0.88 NFKB1 (0.39) P2RX7GAAMAPTKLK7NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119677728-A Process and intermediates for the preparation of nemaltevir 辉瑞大药厂 2025-03-21 CN disclosed