SCHEMBL31367053

SCHEMBL31367053

C[Si](C)(C)c1cc(Br)cc(C=O)c1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
ERN1 O75460 2/20 0.31
ALDH1A3 P47895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1988693 0.77 CYP3A4 (0.30)
SCHEMBL708554 0.77 ALDH1A1 (0.56) ALDH1A1ERN1ALDH1A3
SCHEMBL1585428 0.77 CYP3A4 (0.30)
SCHEMBL646947 0.77 ALDH1A1 (0.56) ALDH1A1ERN1ALDH1A3
SCHEMBL14359452 0.75 KDM4E (0.32) ERN1
SCHEMBL30667909 0.71 ALDH1A1 (0.46) ALDH1A1ERN1ALDH1A3
SCHEMBL1996468 0.71 ALDH1A1 (0.46) ALDH1A1ERN1ALDH1A3
SCHEMBL29411752 0.71 UNG (0.47) ALDH1A1
SCHEMBL5013704 0.70 PRKDC (0.36) ERN1
SCHEMBL12815868 0.69 ALDH1A1 (0.37) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4733297-A1 INTEGRIN-INHIBITING SMALL MOLECULE COMPOUND Antibody Therapeutics, Inc. (JP) 2026-04-29 EP disclosed
WO-2024262620-A1 INTEGRIN-INHIBITING SMALL MOLECULE COMPOUND 株式会社抗体医学研究所 2024-12-26 WO disclosed