Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 5/20 | 0.45 |
| ▸ | IL1B | P01584 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 10/20 | 0.43 |
| ▸ | CCNK | O75909 | 10/20 | 0.43 |
| ▸ | CDK9 | P50750 | 10/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 10/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.43 |
| ▸ | CDK2 | P24941 | 9/20 | 0.43 |
| ▸ | CDK7 | P50613 | 2/20 | 0.41 |
| ▸ | CCNH | P51946 | 2/20 | 0.41 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31367806 | 0.80 | BRD4 (0.44) | CHEK1IL1BCCNT1CCNKCDK9 | |
| SCHEMBL28675000 | 0.76 | IL1B (0.49) | IL1BBPTF | |
| SCHEMBL2053536 | 0.74 | CHEK1 (0.51) | CHEK1IL1BCCNT1CCNKCDK9 | |
| SCHEMBL29270331 | 0.73 | IL1B (0.48) | CHEK1IL1BCCNT1CCNKCDK9 | |
| Hydrochloric Acid SCHEMBL31367812 | 0.72 | IL1B (0.47) | CHEK1IL1BCCNT1CCNKCDK9 | |
| SCHEMBL30626302 | 0.72 | CCNK (0.60) | CHEK1CCNT1CCNKCDK9CDK12 | |
| SCHEMBL25258456 | 0.68 | IDH2 (0.56) | CHEK1CCNT1CCNKCDK9CDK12 | |
| SCHEMBL28312479 | 0.68 | IDH2 (0.56) | CHEK1CCNT1CCNKCDK9CDK12 | |
| SCHEMBL25222649 | 0.68 | IDH2 (0.56) | CHEK1CCNT1CCNKCDK9CDK12 | |
| SCHEMBL17797536 | 0.68 | KMT2A (0.70) | CHEK1CCNT1CCNKCDK9CDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119300833-A | Novel compounds | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |