Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 11/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 8/20 | 0.48 |
| ▸ | BPTF | Q12830 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22655107 | 0.80 | IL1B (0.60) | IL1BKAT2BBPTFNLRP3 | |
| SCHEMBL22655109 | 0.80 | IL1B (0.60) | IL1BKAT2BBPTFNLRP3 | |
| SCHEMBL31367809 | 0.76 | CHEK1 (0.45) | IL1BBPTF | |
| SCHEMBL22654862 | 0.75 | IL1B (0.66) | IL1BNLRP3 | |
| SCHEMBL22654864 | 0.75 | IL1B (0.66) | IL1BNLRP3 | |
| SCHEMBL15951534 | 0.74 | CDK7 (0.51) | IL1BKAT2BBPTFNLRP3 | |
| SCHEMBL25798976 | 0.73 | IL1B (0.61) | IL1BNLRP3 | |
| SCHEMBL30214886 | 0.73 | KAT2B (0.50) | IL1BKAT2BBPTFNLRP3 | |
| SCHEMBL30101069 | 0.72 | KAT2B (0.44) | IL1BKAT2BBPTFNLRP3 | |
| SCHEMBL30213879 | 0.71 | KAT2B (0.57) | KAT2BBPTFNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113784957-A | NLRP3 inflammasome inhibitor | 诺华股份有限公司 | 2021-12-10 | — | — | CN | disclosed |