Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31367977 | 1.00 | NLRP3 (0.45) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL31368007 | 0.90 | NLRP3 (0.42) | NLRP3KMT2AMEN1SMN1; SMN2PIM1 | |
| SCHEMBL31367980 | 0.90 | NLRP3 (0.42) | NLRP3KMT2AMEN1SMN1; SMN2PIM1 | |
| SCHEMBL31368006 | 0.90 | NLRP3 (0.42) | NLRP3KMT2AMEN1SMN1; SMN2PIM1 | |
| SCHEMBL31367989 | 0.87 | PIM1 (0.39) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL31367976 | 0.86 | KMT2A (0.41) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL31367971 | 0.80 | KMT2A (0.38) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL29294062 | 0.80 | NLRP3 (0.69) | NLRP3KMT2ATSHRMEN1HSD17B10 | |
| SCHEMBL31367994 | 0.79 | ADORA1 (0.42) | KMT2ATSHRMEN1SMN1; SMN2ADORA3 | |
| SCHEMBL31368000 | 0.77 | PDE2A (0.44) | KMT2AMEN1SMN1; SMN2ADORA3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092051-A1 | NLRP3 MODULATORS AND USE THEREOF | Bioentropy Inc. (US) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092051-A1 | NLRP3 MODULATORS AND USE THEREOF | NLRP3, NLRP1, NOD1 | NLRP3 1/4885KMT2A 1509/4885TSHR 2991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.