Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736593 | 0.91 | ALDH1A1 (0.50) | SIGMAR1OPRM1CRBNGRM5ALDH1A1 | |
| SCHEMBL737660 | 0.74 | HRH3 (0.49) | SIGMAR1OPRM1ALDH1A1KCNH2 | |
| SCHEMBL13079376 | 0.72 | GRM5 (0.62) | CRBNGRM5NPY5RCYP1A2KCNH2 | |
| SCHEMBL736355 | 0.71 | OPRM1 (0.38) | SIGMAR1OPRM1GRM5ALDH1A1HPGD | |
| SCHEMBL6405329 | 0.71 | CRBN (0.49) | CRBNALDH1A1HPGDHSD17B10PDCD1 | |
| SCHEMBL738190 | 0.70 | NPY5R (0.52) | GRM5ALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL28480423 | 0.70 | CYP1A2 (0.51) | CRBNALDH1A1HPGDHSD17B10USP2 | |
| SCHEMBL14094863 | 0.70 | GRM5 (0.50) | SIGMAR1OPRM1GRM5NPY5RCYP1A2 | |
| SCHEMBL3741402 | 0.70 | GRM5 (0.50) | SIGMAR1OPRM1GRM5NPY5RCYP1A2 | |
| SCHEMBL3740531 | 0.70 | GRM5 (0.50) | SIGMAR1OPRM1GRM5NPY5RCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739685-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | Janssen Pharmaceutica NV (BE) | 2026-05-13 | — | — | EP | claimed |
| WO-2025008061-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | JANSSEN PHARMACEUTICA NV (BE) | 2025-01-09 | — | — | WO | claimed |