Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Avocatin A SCHEMBL10060809 | 1.00 | USP2 (1.00) | USP2MAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| Avocatin A SCHEMBL898834 | 1.00 | USP2 (1.00) | USP2MAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| Avocadyne Acetate SCHEMBL25216029 | 0.90 | USP2 (1.00) | USP2MAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL15944389 | 0.86 | USP2 (0.75) | USP2MAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL4948952 | 0.82 | USP2 (0.70) | USP2MAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL20063076 | 0.81 | USP2 (0.79) | USP2MAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL29497636 | 0.81 | USP2 (0.67) | USP2MAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL13054629 | 0.81 | USP2 (0.68) | USP2MAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL1965555 | 0.81 | USP2 (0.68) | USP2MAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL27881284 | 0.81 | USP2 (0.68) | USP2MAPTCYP3A4ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024263996-A2 | COMPOUNDS AND METHODS FOR TREATING AGAINST NEMATODE INFECTIONS AND METHODS FOR COMPOUND DISCOVERY FOR SAME | NEW YORK UNIVERSITY (US) | 2024-12-26 | — | — | WO | disclosed |