Sugi Predict

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Avocatin A

Avocatin A

SCHEMBL898834

C=CCCCCCCCCCCCC(O)CC(O)COC(C)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 5/20 1.00
▸ MAPT P10636 5/20 1.00
▸ CYP3A4 P08684 4/20 1.00
▸ ALDH1A1 P00352 4/20 1.00
▸ SMN1; SMN2 Q16637 2/20 1.00
▸ HPGD P15428 1/20 1.00
▸ MEN1 O00255 1/20 0.61
▸ TP53 P04637 1/20 0.61
▸ MAPK1 P28482 1/20 0.61
▸ KMT2A Q03164 1/20 0.61
▸ LMNA P02545 2/20 0.58
▸ RECQL P46063 1/20 0.58
▸ ABCC4 O15439 1/20 0.36
▸ PLA2G2C Q5R387 1/20 0.35
▸ CYP2C9 P11712 1/20 0.34
▸ DGKA P23743 1/20 0.34
▸ PRKCA P17252 1/20 0.34
▸ LPAR2 Q9HBW0 2/20 0.34
▸ LPAR3 Q9UBY5 2/20 0.34
▸ LPAR1 Q92633 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Avocatin A SCHEMBL31368575 1.00 USP2 (1.00) USP2MAPTCYP3A4ALDH1A1SMN1; SMN2
Avocatin A SCHEMBL10060809 1.00 USP2 (1.00) USP2MAPTCYP3A4ALDH1A1SMN1; SMN2
Avocadyne Acetate SCHEMBL25216029 0.90 USP2 (1.00) USP2MAPTCYP3A4ALDH1A1SMN1; SMN2
SCHEMBL15944389 0.86 USP2 (0.75) USP2MAPTCYP3A4ALDH1A1SMN1; SMN2
SCHEMBL4948952 0.82 USP2 (0.70) USP2MAPTCYP3A4ALDH1A1SMN1; SMN2
SCHEMBL20063076 0.81 USP2 (0.79) USP2MAPTCYP3A4ALDH1A1SMN1; SMN2
SCHEMBL29497636 0.81 USP2 (0.67) USP2MAPTCYP3A4ALDH1A1SMN1; SMN2
SCHEMBL13054629 0.81 USP2 (0.68) USP2MAPTCYP3A4ALDH1A1SMN1; SMN2
SCHEMBL1965555 0.81 USP2 (0.68) USP2MAPTCYP3A4ALDH1A1SMN1; SMN2
SCHEMBL27881284 0.81 USP2 (0.68) USP2MAPTCYP3A4ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4679087-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 — — EP claimed
WO-2024263996-A2 COMPOUNDS AND METHODS FOR TREATING AGAINST NEMATODE INFECTIONS AND METHODS FOR COMPOUND DISCOVERY FOR SAME NEW YORK UNIVERSITY (US) 2024-12-26 — — WO claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 — — CN claimed
US-20230003721-A1 MITOTHERAPEUTICS FOR THE TREATMENT OF BRAIN DISORDERS THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2023-01-05 — — US claimed
EP-2661266-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES Elcelyx Therapeutics, Inc. (US) 2013-11-13 — — EP claimed
EP-2467030-B1 ORGANIC COMPOUNDS ENHANCING THE UMAMI TASTE GIVAUDAN SA (CH) 2013-07-03 — — EP claimed
US-20120231140-A1 Organic Compounds GIVAUDAN SA (CH) 2012-09-13 — — US claimed
WO-2012094636-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES ELCELYX THERAPEUTICS, INC. (US) 2012-07-12 — — WO claimed
EP-2467030-A1 ORGANIC COMPOUNDS Givaudan SA (CH) 2012-06-27 — — EP claimed
US-20110250154-A1 COSMETIC COMPOSITIONS COMPRISING POLYHYDROXYLTATE FATTY ALCOHOLS AND DERIVATIVES AND USES THEREOF POLYOL BIOTECH LTD (IL) 2011-10-13 — — US claimed
US-20110217251-A1 THERAPEUTIC COMPOSITIONS COMPRISING POLYHYDROXYLTATE FATTY ALCOHOL DERIVATIVES AND USES THEREOF MERETZKI SHAI 2011-09-08 — — US claimed
EP-2340089-A2 COSMETIC COMPOSITIONS COMPRISING POLYHYDROXYLATED FATTY ALCOHOLS AND DERIVATIVES AND USES THEREOF Polyol Biotech Ltd. (IL) 2011-07-06 — — EP claimed
EP-2334293-A2 COMPOSITIONS COMPRISING POLYHYDROXYLTATE FATTY ALCOHOL DERIVATIVES AND THE THERAPEUTIC USES Meretzki, Shai (IL) 2011-06-22 — — EP claimed
WO-2011020908-A1 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2011-02-24 — — WO claimed
WO-2010026595-A2 COSMETIC COMPOSITIONS COMPRISING POLYHYDROXYLTATE FATTY ALCOHOLS AND DERIVATIVES AND USES THEREOF POLYOL BIOTECH LTD. (IL) 2010-03-11 — — WO claimed
WO-2010026596-A2 COMPOSITIONS COMPRISING POLYHYDROXYLTATE FATTY ALCOHOL DERIVATIVES AND THE THERAPEUTIC USES MERETZKI SHAI (IL) 2010-03-11 — — WO claimed
US-20100034944-A1 Use of Avocado Derivatives in Flavor Applications INTERNATIONAL FLAVORS & FRAGRANCES INC. 2010-02-11 — — US claimed
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 — — US disclosed
US-6133313-A SPECIFIED AVOCADOFURANS SUCH AS 2-(TETRADECYL)FURAN, 2-(PENTADECYL)FURAN, 2-(HEXADECYL)FURAN, 2-(HEPTADECYL)FURAN, 2-(OCTADECYL)FURAN, 2-(1E-PENTADECENYL)FURAN, DERIVED FROM IDIOBLAST OIL CELLS OF AVOCADO; CONTROLLING SPODOPTERA EXIGUA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-10-17 — — US disclosed
US-4600593-A IMMERSION IN OIL, CUTTING CAL-FLO CORPORATION (US) 1986-07-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120231140-A1 Organic Compounds TAS1R1, TAS1R2, TAS2R1 USP2 3604/4885MAPT 2996/4885CYP3A4 709/4885
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL USP2 3027/4885MAPT 2113/4885CYP3A4 3591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.